Collin M. Stultz

Shores Salter and Stultz’s efforts to help a Boston Marathon bombing survivor in the immediate aftermath of the attack are described in the 2017 book Perfect Strangers.

Stultz was featured in the 2012 book The Human Face of Big Data, highlighting the software he and co-workers developed, which uses electrocadiographic data to identify patients at high risk for a heart attack.

Stultz began his career in computational biophysics, modeling the structure and function of flexible proteins that play a role in a number of common human diseases. His early research focused on building and applying computational tools to improve understanding of disease processes at the molecular level. His work in this area has involved using a combination of both computational/theoretical models coupled with biochemical experiments, which are designed to test and refine these models. Most notably, Stultz’ research group has developed methods for analyzing and modeling intrinsically disordered proteins (IDPs) that are involved in neurodegenerative disorders. In the mid 2010s, he and his coworkers developed a novel method for modeling IDPs that uses Bayesian statistics to quantify the uncertainty in the underlying structural ensemble. Stultz and his lab have also developed a variational Bayes’ method that enables them to apply these methods to larger systems in a fraction of the CPU time that would be required using a standard Bayes’ formalism.

Stultz has received several honors in recognition of his work. These include a James Tolbert Shipley Prize from Harvard Medical School, a Burroughs Wellcome Fund Career Award (2003), the Irving London Teaching Award (2006), the W. M. Keck Career Development Professorship in Biomedical Engineering from MIT (2007), a Career Award from the National Science Foundation (2008), a Renée Finn Faculty Research Innovation Fellowship (2014). He was inducted into the American Institute for Medical and Biological Engineering College of Fellows. for "ground-breaking contributions to the understanding of protein function in health and disease".

Stultz joined Harvard Medical School as a Clinical Fellow in 1997, becoming a Research Fellow in 2000. At the same time, he also worked as an Intern, Resident and Cardiology Fellow at the Brigham & Women's Hospital. He then joined MIT in 2003 as a Postdoctoral Fellow and became an Assistant Professor in 2004. He was subsequently, appointed the Keck Associate Professor of Biomedical Engineering in 2007. In 2014, Stultz became Full Professor. Stultz was also appointed to the Committee on Higher Degrees in Biopyshics at Harvard University in 2004 and joined the cardiology staff at the Massachusetts General Hospital in 2017.

Stultz received his A.B. magna cum laude in Mathematics and Philosophy from Harvard College in 1988. He then went on to receive a M.D. magna cum laude from Harvard Medical School and a Ph.D. in Biophysics from Harvard University, both in 1997. His Ph.D. thesis work was done in the laboratory of Nobelist Martin Karplus.