Regina Cassandra

In 2020, she signed a Telugu cop drama, a remake of the Korean movie Midnight Runners along with Nivetha Thomas.

In 2013 she had two Tamil releases, Kedi Billa Killadi Ranga by Pandiraj, in which she was one of the two lead actresses, and Nirnayam in which she played a vital role. Although the former proved successful at the box office, she did not sign more films in Tamil and instead shifted her focus to Telugu films. Kotha Janta directed by Maruthi was Regina's first 2014 release. She received positive response for her performance in the film. Deccan Chronicle wrote, "The star of the film is undoubtedly Regina Cassandra. She looks cute and bubbly and delivers a delightful performance. She has done her character with ease and with the right expressions". Her next releases were Ra Ra... Krishnayya, which saw her reuniting with Sundeep Kishan, and Power in which she played a Bengali girl. Power was declared as one of the biggest blockbusters of the year and this is the biggest hit in Regina's career till date. She played the lead role opposite Sai Dharam Tej in Pilla Nuvvu Leni Jeevitam directed by AS Ravi Kumar Chowdary.

However the film's low-key release meant that the film failed to gain attention, so she took time out from films and then went on to graduate in psychology from Women's Christian College, Chennai and took another year off before taking a final call on joining movies. During her break she also acted in several short films, including Balaji Mohan's Kadhalil Sodhappuvadhu Yeppadi alongside Adith Arun, which was later made into a feature film in 2012 under the same name.

In 2012, she appeared in Shiva Manasulo Shruti by Tatineni Sathya, which was a remake of the 2009 Tamil film Siva Manasula Sakthi. She was next seen in the Telugu romantic-comedy, Routine Love Story, alongside Sundeep Kishan, which she signed even before her first release in Telugu.