Rosalyn Sussman Yalow

Yalow died May 30, 2011, in the Bronx, New York. She was predeceased by her husband, and survived by two children, Benjamin and Elanna, and two grandchildren. She was buried at Mount Moriah Cemetery in Fairview, New Jersey.

In 1993, Yalow was inducted into the National Women's Hall of Fame.

In 1988, Yalow received the National Medal of Science, which is given to American individuals who deserve the highest honor in science and technology.

In 1986, Yalow was awarded the A. Cressy Morrison Award in Natural Sciences of the New York Academy of Sciences, which is offered by Mr. Abraham Cressy Morrison to individuals with superlative papers on a scientific subject within the field of The New York Academy of Sciences and its Affiliated Societies.

In 1978, Yalow was elected a Fellow of the American Academy of Arts and Sciences, which provides an opportunity for an early-career professional with training in science or engineering to learn about a career in public policy and administration.

In 1977, Yalow was the sixth individual woman (seventh overall, considering Marie Curie's two wins), and first American-born woman, to win the Nobel Prize in a scientific field. She was also the second woman in the world to win in the physiology or medicine category (the first was Gerty Cori). Yalow was honored for her role in devising the radioimmunoassay technique, along with Roger Guillemin and Andrew V. Schally for their research in another field. By measuring substances in the human body, the screening of the blood of donors for such diseases as hepatitis was made possible. Radioimmunoassay can be used to measure a multitude of substances found in tiny quantities in fluids within and outside of organisms (such as viruses, drugs and hormones). The list of substances is endless, but specifically, it allowed blood donations to be screened for various types of hepatitis. The technique can also be used to identify hormone-related health problems. Further, it can be used to detect in the blood many foreign substances including some cancers. Finally, the technique can be used to measure the effectiveness of dose levels of antibiotics and drugs.

In 1977, Yalow received the Golden Plate Award of the American Academy of Achievement.

In 1975, Yalow and Berson (who had died in 1972) were awarded the American Medical Association Scientific Achievement Award, which is a gold medallion award presented to individuals on special occasions in recognition of their outstanding work in scientific achievement.

In 1972, Yalow was awarded the William S. Middleton Award for Excellence in Research, which is the highest honor awarded annually by the Biomedical Laboratory Research and Development Service to senior biomedical research scientists in recognition of their outstanding scientific contributions and achievements, pertaining to the healthcare of veterans.

Also in 1972, she was given the Koch Award of the Endocrine Society, which awards individuals for their dedication to excellence in research, education and clinical practice in the field of endocrinology.

Despite its huge commercial potential, Yalow and Berson refused to patent the method. In 1968, Yalow was appointed as a research professor in the Department of Medicine at Mount Sinai Hospital, where she later became the Solomon Berson Distinguished Professor at Large. Yalow also had a passion for the next generation of researchers. She acted as a mentor figure to scientists from around the world, many of whom came to share her passion for investigative endocrinology research. One of these mentees, Dr. Narayana Panicker Kochupillai, went on to become a leading endocrinology researcher in India, studying thyroid hormones and iodine deficiency. In this way, Yalow's legacy in endocrinology was carried on. A fitting title for Rosalyn Yalow may well be "the Mother of Endocrinology."

In 1961, Yalow won the Eli Lilly Award of the American Diabetes Association, which provides scholarships for up to 100 scholars to attend Scientific Sessions, the world's largest scientific and medical conference focused on diabetes and its complications. Additionally, it provides the education and training for these scholars to serve as faculty for professional education programs and to clinically manage the disease.

The Veteran's Administration wanted to establish research programs to explore medical uses of radioactive substances. By 1950, Yalow had equipped a radioisotope laboratory at the Bronx VA Hospital and decided to leave teaching to finally devote her attention to full-time research. There she collaborated with Solomon Berson to develop radioimmunoassay, a radioisotope tracing technique that allows the measurement of tiny quantities of various biological substances in human blood as well as a multitude of other aqueous fluids. Originally used to study insulin levels in diabetes mellitus, the technique has since been applied to hundreds of other substances – including hormones, vitamins and enzymes – all which had been present in quantities or concentrations that were previously too small to detect. Without the contributions of Yalow to the work of accurate hormone measurement, it was impossible to diagnose various hormone-related conditions and endocrine diseases like type 1 diabetes.

Yalow's first job after teaching and taking classes at the University of Illinois at Champaign-Urbana graduate school was as an assistant electrical engineer at Federal Telecommunications Laboratory. She again found herself to be the only woman employee. In 1946, she returned to Hunter College to teach physics and consequently influenced many women, most notably a young Mildred Dresselhaus: Yalow was responsible for steering the future "Queen of Carbon Science" away from primary school teaching and into a research career. She remained a physics lecturer from 1946 to 1950, although by 1947, she began her long association with the Veterans Administration by becoming a consultant to the Bronx Veteran's Administration Hospital.

The following year she became the first female recipient and first nuclear physicist of the Albert Lasker Award for Basic Medical Research. Established by Albert and Mary Lasker in 1945, the award is intended to celebrate scientists who have made fundamental biological discoveries and clinical advances that improve human health.

She married fellow student Aaron Yalow, the son of a rabbi, in June 1943. They had two children, Benjamin and Elanna Yalow, and kept a kosher home. Yalow did not believe in "balancing her career with her home life" and instead incorporated her home life wherever she could in her work life. However, she viewed the traditional roles of a homemaker as a priority, and devoted herself to traditional duties associated with motherhood and being a wife.

Yalow knew how to type, and was able to get a part-time position as a secretary to Dr. Rudolf Schoenheimer, a leading biochemist at Columbia University's College of Physicians and Surgeons. She did not believe that any respectable graduate school would admit and financially support a woman, so she took another job as a secretary to Michael Heidelberger, another biochemist at Columbia, who hired her on the condition that she studied stenography. She graduated from Hunter College in January 1941.

The month after graduating from Hunter College in January 1941, Rosalyn Sussman Yalow was offered a position as a teaching assistant in the physics department of the University of Illinois at Urbana-Champaign. Gaining acceptance to the physics graduate program in the College of Engineering at the University of Illinois was one of the many hurdles she had to overcome as a woman in her field. Powerful male figures controlled opportunities for training, recognition, promotion, and many aspects of development in the field of science, and especially physics.

When Yalow entered the university in September 1941, she was the only woman in the faculty, which comprised 400 professors and teaching assistants. She was the first woman since 1917 to attend or teach at this engineering college. Yalow credited her position at the prestigious graduate school to the shortage of male candidates during World War II. Being surrounded by gifted men made her aware of a wider world in science. They recognized her talent, they encouraged her, and they supported her. They were in a position to help her succeed.

Rosalyn Sussman Yalow (July 19, 1921 – May 30, 2011) was an American medical physicist, and a co-winner of the 1977 Nobel Prize in Physiology or Medicine (together with Roger Guillemin and Andrew Schally) for development of the radioimmunoassay technique. She was the second woman (after Gerty Cori), and the first American-born woman, to be awarded the Nobel Prize in Physiology or Medicine.

A few years later, she received an offer to be a teaching assistant in physics at the University of Illinois at Urbana-Champaign. She received this offer partially because World War II had just begun and many men went off to fight, and the University opted to offer women education and jobs to avoid being shut down. At the University of Illinois at Urbana-Champaign, she was the only woman among the department's 400 members, and the first since 1917. Yalow earned her PhD in 1945. The next summer, she took two tuition-free physics courses under government auspices at New York University.