Shyamala Gopalan

Shyamala died of colon cancer in Oakland on February 11, 2009 at aged 70. She requested that donations be made to the organization Breast Cancer Action. Later in 2009, Kamala Harris carried her ashes to Chennai on the southeastern coast of peninsular India and scattered them in the Indian Ocean waters.

In the fall of 1962, at a meeting of the Afro-American Association—a students' group at Berkeley whose members would go on to give structure to the discipline of Black studies, propose the holiday of Kwanzaa, and help establish the Black Panther Party—Shyamala met a graduate student in economics from Jamaica, Donald J. Harris, who was that day's speaker. According to Donald Harris, who is now an emeritus professor of economics at Stanford University, “We talked then, continued to talk at a subsequent meeting, and at another, and another." In 1963 they were married without following the convention of introducing Harris to Shyamala's parents beforehand or having the ceremony in her hometown. In the later 1960s, Donald and Shyamala took their daughters, Kamala, then four or five years old, and Maya, two years younger, to newly independent Zambia, where Shyamala's father, Gopalan, was on an advisory assignment. After Shyamala divorced Donald in the early 1970s, she took her daughters to India several times to visit her parents in Chennai, where they had retired.

A gifted singer of Carnatic music, Shyamala won a national competition in it as a teenager. She studied for a BSc in Home Science at Lady Irwin College in Delhi. Her father thought the subject—which taught skills considered helpful in homemaking—was a mismatch for her abilities; her mother expected the children to seek careers in medicine, engineering, or the law. In 1958, aged 19, Shyamala unexpectedly applied to a master's program in nutrition and endocrinology at the University of California, Berkeley, and was accepted. Her parents used some of their retirement savings to pay her tuition and board during the first year. Not having a phone line at home, they communicated with her after her arrival in the US by aerogram. She earned a PhD in nutrition and endocrinology at UC Berkeley in 1964. Shyamala's dissertation, which was supervised by Richard L. Lyman, was titled The isolation and purification of a trypsin inhibitor from whole wheat flour.

Gopalan Shyamala (December 7, 1938 – February 11, 2009) was a biomedical scientist at the Lawrence Berkeley National Laboratory, whose work in isolating and characterizing the progesterone receptor gene stimulated advances in breast biology and oncology. She was the mother of Vice President of the United States Kamala Harris and Maya Harris, a lawyer and political commentator.

Shyamala was born on December 7, 1938, in Madras, Madras Province, British India (present-day Chennai, Tamil Nadu, India) to Rajam Gopalan and P. V. Gopalan, a civil servant. Her parents were from two villages near the town of Mannargudi in Madras Province. According to The Los Angeles Times, "Gopalan was a Tamil Brahmin, part of a privileged elite in Hinduism’s ancient caste hierarchy". According to Shyamala's brother, Balachandran, their parents were broad-minded in raising the children, all of whom led somewhat unconventional lives. Gopalan began his professional life as a stenographer, rising through the ranks in the civil service, moving the family every few years between Madras, New Delhi, Bombay, and Calcutta.