Talia Castellano

Castellano died at the Arnold Palmer Hospital for Children in Orlando, Florida, on July 16, 2013, about a month before her 14th birthday, after spending the last three months of her life in palliative care. After years of grueling treatment and with the disease metastasized, she declined any further proactive treatment. An announcement was made soon after the time of Castellano's death, on the Angels For Talia Facebook page.

On July 16, 2013, the day Castellano died, a video was posted on her YouTube channel by her older sister Mattia, who explained how she wanted some of Castellano's old friends to help carry out Talia's legacy, by completing the 13-year-old's bucket list. She also stated her determination to create a makeup line for Talia, and a clothing line, which never carried through. Back at the time of her death, friends and family of Castellano posted pictures of things she wanted to do as part of her bucket list, such as getting a tattoo and having "a huge water balloon fight." Castellano's YouTube channel and Twitter are now controlled by her elder sister and mother, with occasional updates, videos, and promotions.

The YouTube Rewind of 2013 was dedicated to Castellano. At the end of the video, the words, "For Talia Joy, who still inspires us" are handwritten.

In September 2012, she appeared on The Ellen DeGeneres Show, and was announced as a face for CoverGirl cosmetics. She appeared in CoverGirl magazine ads with her slogan "Makeup is my wig".

When first diagnosed, Castellano bonded with family friend Tammy DeLaRosa, who was also a cancer survivor. Delarosa taught her how to use makeup. On August 27, 2011, she uploaded her first makeup tutorial, "Crazy eyeliner" to YouTube where it gained over 30,000 views.

When she was 7 years old, Castellano began experiencing fevers and abdominal pain. When an X-ray on February 14, 2007 showed unusual anatomical displacements in her chest, she was diagnosed with neuroblastoma, a rare pediatric cancer of the peripheral nervous system. She underwent various types of therapies and treatments and was initially declared cancer-free, but relapsed three times in the next six years. During that time she was diagnosed with myelodysplastic syndrome (previously known as preleukemia) and progressive neuroblastoma. There are no known treatments to tackle both cancers at the same time. Although she was given only months to live, a novel drug therapy provided her with an additional 11 months.

Talia Castellano (August 18, 1999 – July 16, 2013) was a Covergirl and an American Internet “celebrity” known for her YouTube channel "TaliaJoy18" that featured her makeup tutorials. Her channel was mainly dedicated to makeup, fashion and cancer vlogs where she would discuss neuroblastoma and leukemia, the diseases she battled for six years. At the time of Castellano's death, her channel had more than 750,000 subscribers and 45 million video views. As of May 2018, her YouTube channel has more than 1,480,000 subscribers with over 94 million video views.

Castellano was born on August 18, 1999, in Orlando, Florida, and grew up in and around central Florida with her mother, Desiree Castellano who is of Costa Rican descent and in New York City with her father, Marc Winthrop,a American musician on drums. She had three siblings: Kaitlyn, Jackson Winthrop, and Mattia Castellano.