Derrius Guice

Guice made his debut with the Redskins in Week 1 against the Philadelphia Eagles. In the game, Guice rushed 10 times for 18 yards and caught 3 passes for 20 yards, but left the game with an injury to his right knee. The Redskins would go on to lose the game 27-32. It was later revealed that Guice had suffered a torn meniscus, requiring surgery, with him being placed on injured reserve on September 13, 2019. He was designated for return from injured reserve on October 28, 2019, and began practicing again with the team. He was activated off injured reserve on November 7. In Week 11 against the New York Jets, Guice rushed seven times for 24 yards and caught one pass for a 45-yard touchdown in the 34–17 loss. In Week 13 against the Carolina Panthers, Guice rushed 10 times for 129 yards and two touchdowns in the 29–21 win. The following week, he suffered an MCL sprain and was placed on injured reserve on December 10, 2019.

In January 2018, Guice announced that he would forego his senior year at LSU in favor of the 2018 NFL Draft. Guice attended LSU's pro day in April 2018, but opted to stand on his combine numbers and only performed positional drills. At the conclusion of the pre-draft process, Guice was projected to be a first or second round pick by NFL draft experts and scouts. He was ranked among the best running backs of the 2018 class, Predicted as a first round pick before the draft, Guice reportedly had his draft stock fall due to questions about his character and other incidents during the drafting process, such as an alleged verbal altercation between himself and Howie Roseman, executive of the Philadelphia Eagles. Roseman and other Eagles personnel denied it took place, with Guice stating that the incident, as well as other rumors of him being lazy, immature, and dishonest, were not true. Another issue allegedly occurred at the NFL Combine, where Guice claimed that he was asked if he liked men during an interview with a team, as well as if his mother "sells herself". The NFL later investigated the claims, but found no proof it had happened.

Guice was eventually drafted in the second round, 59th overall, by the Washington Redskins. On May 10, 2018, Guice signed a four-year, US$ 4.54 million contract with the team. In the first preseason game of his rookie year, Guice sustained a torn ACL, which ended his season.

In November 2016, Guice's brother, Derrick, was arrested and charged with attempted second degree murder following an incident where he was the driver of two gunmen who shot at a man on his porch in Baton Rouge. Following a visit to the Mary Bird Perkins Cancer Center in June 2018, Guice set up a GoFundMe crowdfunding campaign for cancer research, raising over US$ 21,000 in a week.

Guice spent his true freshman year at LSU in 2015 as a backup to Leonard Fournette. He played in all 12 games, rushing for 436 yards on 51 carries with three touchdowns. Guice entered his sophomore season again as a backup to Fournette. He started his first career game in place of an injured Fournette during the team's second game of the season and ran for 155 yards and a touchdown on 19 carries. Against the Arkansas Razorbacks on November 12, Guice rushed for 252 yards, which was the second most in a game in school history. The total included a school-record 96-yard touchdown run in the fourth quarter. Two weeks later, against Texas A&M, he set the school single-game record by rushing for 285 yards, breaking the previous mark set by Fournette earlier in the season by one yard. He became only the fourth running back in Southeastern Conference history to record multiple 250-yard rushing performances in a career, following Bo Jackson, Herschel Walker, and Moe Williams. He was named to the Associated Press first-team All-SEC team following the regular season.

As a senior, he rushed for 1,341 yards with 21 touchdowns. Catholic went 9–2 on the season and lost 25–23 to New Orleans Brother Martin in the LHSAA Division I quarterfinals at BREC Memorial Stadium, after Guice was stopped on a two-point conversion that would have tied the game. After his senior season, Guice played in the U.S. Army All-American Bowl and was awarded the Pete Dawkins Trophy. Guice was rated by Rivals.com as a five-star recruit and was ranked as the second best high school running back at the time, behind Damien Harris. He committed to Louisiana State University (LSU) to play college football, fulfilling a promise he made to his father before his death.

Derrius Guice (pronounced /ɡ aɪ s / ) (born June 21, 1997) is an American football running back for the Washington Redskins of the National Football League (NFL). He played college football at LSU, and was drafted by the Redskins in the second round of the 2018 NFL Draft. He is the only player in Southeastern Conference (SEC) history with three career games of 250 or more rushing yards.

Guice was born in a poverty-stricken section in Baton Rouge, Louisiana, known as "the Bottom", to parents Derek and Beulah Guice on June 21, 1997. On May 3, 2003, Derek was killed after being involved in a fight at a Denny's restaurant, with Guice learning of it after seeing the scene on the news. As a way to deal with his emotions and not feeling safe at home, Guice focused his life around football, with his powerful running style being described as "running angry".