Jacksepticeye

McLoughlin uploads once a day to his YouTube channel, usually a Let's Play or vlog style of video. McLoughlin has claimed an inclusive community is an important part of the Jacksepticeye channel stating "one of the main things I wanted to do on YouTube is to keep people together". McLoughlin calls himself the "most energetic video-game commentator on YouTube". McLoughlin has also described his content as an "assault on the senses" that people "either love or hate". In an interview with Irish Independent McLoughlin described the format of his videos as him playing and talking over video games, with a lot of swearing. He has cited his use of swearing as a key aspect to his success saying, "There’s lots of swearing. The more you swear the better. People react very positively to that apparently."

In January 2019, McLoughlin hosted a livestream which raised over $100,000 for the Make-A-Wish Foundation. In May, McLoughlin hosted a fundraising stream for Red Nose Day 2019 raising over $110,000 in nine hours. In January 2020, McLoughlin hosted a livestream which raised over $200,000 in four hours for the bushfires in Australia. In April 2020, McLoughlin hosted a livestream which raised over $650,000 in 12 hours for COVID-19 relief funds. Including subsequent livestreams in collaboration with McLoughlin, the campaign raised over $1.7 million. As of January 2020, since 2017, McLoughlin has raised almost $4 million in total in charity livestreams.

In January 2018, it was announced McLoughlin would produce exclusive content for Twitch as part of a multi-year deal with Disney’s Digital Network. In February 2018, McLoughlin released dates for a US and Canada run of the How Did We Get Here tour. In April 2018, it was announced McLoughlin would be a part of the comedy line-up for the HowTheLightGetsIn Festival. In May 2018, McLoughlin uploaded a video of him and Ryan Reynolds playing the Deadpool video game. In January 2019, McLoughlin signed with WME. In June 2019, it was announced that McLoughlin would be a part of the line-up at the Metarama Gaming + Music Festival alongside acts such as Marshmello, Logic, Ninja, and Overwatch League players.

McLoughlin has been critical of the changing algorithms and policies at YouTube, voicing his dissatisfaction. In April 2018, McLoughlin responded to YouTube pulling ads from "unsuitable content" stating "This is people's careers. To completely switch how you do things and not tell anybody is a sh-ty [sic] thing to do." In May 2018, McLoughlin responded to a surprise algorithm test from YouTube which changed the order of videos displayed in its subscription feed by stating that "People use the subscription tab to mainly avoid this sort of algorithmic behavior. Please keep that to the home page and recommendations."

Throughout 2018, McLoughlin hosted various charity livestreams for charities such as the American Foundation for Suicide Prevention, the Depression and Bipolar Support Alliance, GameChanger, a charity with the stated aim of "[leveraging] technology and innovation to empower patients to play, learn, and socialize", AbleGamers, a charity which creates custom gaming setups for disabled gamers, St. Jude Children's Research Hospital, and Crisis Text Line raising a total of over $1 million for charities in 2018.

McLoughlin co-starred as the antagonist of the second season of the YouTube Red show Scare PewDiePie. However, the season was cancelled before its release due to controversy surrounding PewDiePie. The series was planned to premiere on 9 March 2017.

On 18 February 2017, McLoughlin released a video called "Let's Talk!" to his YouTube channel which discussed PewDiePie being cut from Maker Studios for his use of anti-Semitic imagery. In it, he clarified that while he had tweeted in support of PewDiePie he did not condone his actions and believed he could have been more apologetic. Overall, McLoughlin states, "You can still be friends with someone but not agree with something they do. I don't think the world is that black-and-white."

In June 2017, Polaris, a division of The Walt Disney Company, announced that McLoughlin would be featured on D | XP, a television programming block on the channel Disney XD. The title of the series featuring McLoughlin is Polaris: Player Select. He and YouTuber Strawburry17 hosted the Level Up! games panel at the D23 Expo 2017. In July 2017, it was announced that McLoughlin would be a playable character in the strategic prison-escape game The Escapists 2. In September 2017, McLoughlin was featured on the RTÉ 2 Rich List in the "top 30 under 30" category. McLoughlin toured throughout September–October 2017, in the US with the How Did We Get Here tour, and then returned to the UK and Europe to tour with the Game Grumps for the Ready Player 3 tour.

In January 2016, McLoughlin was one of the initial YouTubers signed under PewDiePie's network, Revelmode.

Throughout 2016 McLoughlin continued to upload 2 videos a day while also making frequent collaborations with other YouTubers, a common series of videos was where he would play prop hunt with fellow YouTubers such as Markiplier, Lordminion777, and Muyskerm. This was also the first year he competed in the "annual" bottle flip challenge against PewDiePie, in this competition they would flip a bottle and whoever's doesn't land, they'll have to look a Reddit 50/50, after the first episode made in December 2016, the tradition was put on hold until they made another in May 2019 and then once again in May 2020.

In December 2016, McLoughlin was a part of the Revelmode charity holiday livestream #Cringemas, with PewDiePie, Markiplier, Emma Blackery and PJ Liguori. The group raised over $1.3 million under the hashtag #EndAIDS, with matching donations from the Gates Foundation and YouTube. In December 2017, McLoughlin hosted two charity streams to raise money for Save The Children, with Blackery and Liguori. In the second stream Blackery revealed that over $260,000 had been raised for the charity.

During July 2014, McLoughlin's channel gained over 57 million views. At the time, his channel had only 800,000 subscribers. By February 2015, the channel had reached one billion views and 3.2 million subscribers.

McLoughlin grew up in Athlone, Ireland where he was given the nickname Jacksepticeye. Whilst at college, McLoughlin was the drummer for the metal band, Raised to the Ground, with whom he released one EP, Risen from the Ashes, in 2009. He currently lives in Brighton, England. In October 2018, McLoughlin announced that he had split from his Danish vlogger girlfriend Signe Hansen, better known as "Wiishu". He posted on Twitter that it was "not an easy decision to make". In March 2019, McLoughlin announced that he is currently in a relationship with Dutch YouTuber Evelien Smolders, formerly known as "GirlGamerGab" but now better known as "Gab Smolders".

McLoughlin joined YouTube on 24 February 2007 but didn't start uploading videos until November 2012 when he started to work on his channel under the name "jacksepticeye", posting gameplay videos. The origin of the name "jacksepticeye" started with his mother, who has always called him Jack, as it's a popular nickname for Sean in Ireland. A childhood friend found out about this and started to also call him Jack as a joke. One day he was playing football and he got accidentally hit in the eye, hard enough that it started bleeding. Over the next few weeks the eye got a bit infected and then his friend dubbed him 'Jack Septic Eye'. In 2013, McLoughlin was mentioned in a PewDiePie video, causing him to gain mass popularity; he went from 2,500 subscribers to 15,000 in four days.

Seán William McLoughlin (born 7 February 1990), better known as Jacksepticeye, is an Irish YouTuber and actor, best known for his vlogs and comedic Let's Play series. As of May 2020, his channel has over 12 billion views and over 24 million subscribers, and is ranked the most-subscribed channel in Ireland. McLoughlin has participated in fundraisers that have raised millions of US dollars for charity.