Johnny DuPree

In 2019, DuPree ran for Secretary of State of Mississippi. He lost the election to Michael Watson.

In 2017, DuPree was defeated in a bid for a fifth consecutive term as mayor, losing to Toby Barker, a Republican member of the state House of Representatives who ran as an independent.

In the 2013 mayoral election, DuPree faced fourth ward councilman Dave Ware, a Republican who ran as an independent, along with three minor candidates in his bid for a fourth term as mayor. In the June 4 election, DuPree was believed to be the winner by 37 votes out of over 9,600 cast, but concerns were raised about possible voter fraud, eligibility of some voters, and the fact that the city clerk left ballots unsecured in city hall the night before the election. Ware filed an election challenge on June 24, and a special judge was appointed by the state Supreme Court to hear the case. The jury initially found in favor of Ware in a 9-3 vote, the bare minimum for a verdict, however after Judge William Coleman polled the jurors, the count shifted to 8-4 and a mistrial was declared.

In the Democratic primary of the 2011 Mississippi gubernatorial election, DuPree faced businessman and future Clarksdale mayor Bill Luckett and two minor candidates. Despite a significant fundraising disadvantage, on August 23, 2011, DuPree defeated Luckett by 179,748 votes (43.6%) to 161,833 (39.2%). He lost to Republican nominee Phil Bryant in the general election on November 8, 2011.

On the Sunday before Hurricane Katrina hit the Gulf Coast in 2005, DuPree was invited to address the congregation of Mt Carmel Baptist Church, where he warned the congregation about the "devastation churning its way across the Gulf of Mexico." In the aftermath of the storm, the city lost power and water for several days. Due to the lack of a response from the Federal Emergency Management Agency (FEMA), the city under DuPree resorted to leasing essential equipment and goods on its own, items such as generators, which would normally be available through federal and state emergency services. Because of Hattiesburg's position as a regional hub and as the first major metropolitan area outside of New Orleans, the city was flooded with thousands of evacuees. In the immediate aftermath of the storm, DuPree's government worked to meet the needs of the displaced evacuees without assistance from federal agencies.

In 2001, DuPree became the first African-American mayor of Hattiesburg after winning 53% of the vote. He was re-elected twice in the next decade. During his first campaign for mayor, DuPree ran on a platform of shoring up education and protecting small business. At the time, Robert Ingram, the executive director of economic development at the University of Southern Mississippi, predicted that DuPree would support locally owned small business while also being active in industrial recruitment. Despite damage to the city resulting from Hurricane Katrina and a global recession, the health of Hattiesburg's small businesses remained steady during DuPree's tenure as mayor. Ingram's predictions for Hattiesburg under the DuPree administration were largely accurate. In 2010, employment statistics showed Hattiesburg registering only 8.6 percent at a time when the state unemployment rate was 11.2 and the national rate was 11.1. Also during DuPree's tenure as mayor, annual crime statistics released by the Hattiesburg Police Department in showed a 10 percent overall decrease in reported crime since 2008.

DuPree entered public service in 1987 when he was appointed to the Hattiesburg Public School Board. A year later, he and his wife established a small business in real estate. In 1991, he was elected to the Forrest County Board of Supervisors where he served for 10 years before running for mayor of Hattiesburg in 2001.

DuPree has been married to Johniece since 1972. They have two daughters, April and Monica and two grandsons, Chandler DuPree Taylor and Chesney DuPree Taylor. His older daughter, April DuPree Taylor (Coustaur Taylor), works at the Department of Communication at the University of South Alabama. His younger daughter, Monica DuPree, is an educator in the Hattiesburg Public School District.

Johnny DuPree (born November 18, 1953) is an American politician and member of the Democratic Party who served as the mayor of Hattiesburg, Mississippi from 2001 to 2017. He was the Democratic Party nominee for Governor of Mississippi in 2011. He was the first African-American major party nominee for Governor in Mississippi since the Reconstruction era. On February 19, 2019, DuPree announced his candidacy for Secretary Of State.