LaDonna Harris

Harris also supported Depp when an ad featuring Depp and Native American imagery, by Dior for the fragrance "Sauvage", was pulled on August 30, 2019, after charges of cultural appropriation and racism.

She was an honorary co-chair of the Women's March on Washington, which took place on January 21, 2017, the day after the inauguration of Donald Trump as president.

Harris endorsed Bernie Sanders for president during the 2016 Democratic presidential primaries.

After reading interviews of the filming of the 2013 movie The Lone Ranger, and that Johnny Depp's reprisal of the role of 'Tonto' would be as a Comanche, Harris decided to adopt Depp as an honorary son, making him an honorary member of her family but not an enrolled member of any tribe. She discussed the idea with her adult children, and they agreed. A unique adoption ceremony took place on May 16, 2012, at Harris's home in Albuquerque, New Mexico, attended by the cultural advisor for The Lone Ranger and an official from the tribe. "Welcoming Johnny into the family in the traditional way was so fitting... He's a very thoughtful human being, and throughout his life and career, he has exhibited traits that are aligned with the values and worldview that Indigenous peoples share", Harris said. Critical coverage of Depp in Indian Country increased after this, including satirical portrayals of Depp by Native comedians.

She has been appointed to many Presidential Commissions, including being recognized by Vice President Al Gore, in 1994, as a leader in the area of telecommunications in his remarks at the White House Tribal Summit. She was a founding member of Common Cause and the National Urban Coalition and is a spokesperson against poverty and social injustice. As an advocate for women's rights, she was a founder of the National Women's Political Caucus.

With the end of her husband's Congressional career, LaDonna Harris moved away from mainstream politics within the Democratic Party. In 1980, as the vice presidential nominee on the Citizens Party ticket with Barry Commoner, Harris added environmental issues to the national debate and future presidential campaigns. Although Harris was the first Indigenous woman to run for vice president, she was replaced on the ballot in Ohio by Wretha Hanson.

She left NICO in 1970 and founded Americans for Indian Opportunity (AIO). From the 1970s to the present, she has presided over AIO, which works to advance the cultural, political and economic rights of Indigenous peoples in the U.S. and around the world. She helped found some of today's leading national Indian organizations including the National Indian Housing Council, Council of Energy Resource Tribes, National Tribal Environmental Council, and National Indian Business Association.

In the 1960s, Harris, as the wife of a United States Senator, lived in Washington, D.C. and was in constant social and political contact with the top echelons of the Democratic Party, up to and including President Lyndon B. Johnson and the First Lady. At the same time, her daughter Kathryn - at the time a university student - was deeply involved in the Anti war movement opposing the Vietnam War, which was conducted by the same President Johnson. Kathryn used to bring home other student activists to stay the night, and used the parental home as an unofficial headquarters where activists prepared for the next day's demonstrations and confrontations with police - with the tacit consent of her parents.

Harris was born Ladonna Vita Tabbytite, in Temple, Oklahoma, to Lilly Tabbytite (Comanche) and Donald Crawford, a non-Native; the couple separated shortly after her birth. She was raised traditionally by her maternal grandparents in a self-governing Indigenous community on a farm near the small town of Walters, Oklahoma. She speaks Comanche as her first language. She learned English when she began attending public school. In 1949, shortly after graduating high school, she married Fred R. Harris. Ladonna supported Fred through college, and was very involved in his campaign for U.S. Senator. In 1964, Fred Harris was elected to the U.S. Senate, and the family, now with three children, relocated from Oklahoma to Washington D.C.

LaDonna Vita Tabbytite Harris (born February 26, 1931) is a Comanche Native American social activist and politician from Oklahoma. She is the founder and president of Americans for Indian Opportunity. Harris was a vice presidential candidate for the Citizens Party in the 1980 United States presidential election alongside Barry Commoner. She was the first Native American woman to run for vice president. In 2018, she became one of the inductees in the first induction ceremony held by the National Native American Hall of Fame.

Currently, she serves on the boards of Advancement of Maori Opportunity, Institute for 21st Century Agoras, National Senior Citizens Law Center, and Think New Mexico. She serves on the advisory boards of the National Museum of the American Indian, American Civil Liberties Union, Delphi International Group, and National Institute for Women of Color.