Sharif Hassan Sheikh Aden

In response, Prime Minister Mohamed released a statement through the state-run Radio Mogadishu commending the military for its rapid response and urging its troops to exercise restraint. He also appealed to the public to calm down, and indicated that "I have seen your expressions and heard your calls[...] You are part of the decision making — what you want must be heard." Additionally, in a press conference, the Premier called for the immediate release of all protestors who had been detained, and stated that his administration would launch an independent investigation into their arrest. Weighing in on the demonstrations, Mogadishu's Mayor Mohamed Nur suggested that "what [the demonstrators] have a problem with is that two people go and decide the fate of this government without considering the feelings of this population", and that putting the issue before Parliament for approval is a more democratic course of action.

On 17 November 2014, Sharif Hassan was elected President of the three region Southwestern State of Somalia.

In February 2012, Sharif Hassan and other Somali government officials met in the northeastern town of Garowe to discuss post-transition political arrangements. After extensive deliberations attended by regional actors and international observers, the conference ended in a signed agreement between the Parliamentary Speaker, TFG President Sharif Ahmed, Prime Minister Abdiweli Mohamed Ali, Puntland President Abdirahman Mohamed Farole, Galmudug President Mohamed Ahmed Alim and Ahlu Sunnah Wal Jama'a representative Khalif Abdulkadir Noor stipulating that: a) a new 225 member bicameral parliament would be formed, with a lower house and an upper house seating 54 Senators; b) 30% of the National Constituent Assembly (NCA) is earmarked for women; c) the President is to be appointed via a constitutional election; and d) the Prime Minister is selected by the President and he/she then names his/her Cabinet. On June 23, 2012, the Somali federal and regional leaders met again and approved a draft constitution after several days of deliberation. The National Constituent Assembly overwhelmingly passed the new constitution on August 1, with 96% voting for it, 2% against it, and 2% abstaining.

On 20 August 2012, Sharif Hassan was among the legislators nominated to the newly established Federal Parliament of Somalia.

After months of political infighting between the Speaker of Parliament Sharif Hassan and President Sharif Ahmed over whether to hold presidential elections in August 2011, the two politicians struck a deal in Kampala on June 9, 2011 to postpone the vote for a new President and parliamentary Speaker for one year in exchange for the resignation of the Premier within a period of thirty days. Overseen by the Ugandan President Yoweri Museveni and the U.N. Special Envoy to Somalia Augustine Mahiga, the signed Kampala Accord would also see the well-regarded technocratic Cabinet that Prime Minister Mohamed had assembled in November 2010 re-composed to make way for a new government. Political analysts have suggested that the agreement may have been a bid on President Sharif Ahmed's part to fend off attempts by the Speaker of Parliament Sharif Hassan to force him from power by pre-emptively "sacrificing" the Premier. Sharif Hassan is also reported to harbor presidential ambitions of his own.

On June 11, 2011, Prime Minister Mohamed released a statement indicating that the Kampala decision ought to be presented in Parliament for debate and appraised according to the laws stipulated in the national constitution. The Premier also stated that he would only step down if lawmakers voted to uphold the accord. This was echoed by the Cabinet, which indicated in a press release that, after having convened to discuss the Kampala decision, the Ministers agreed that the accord must be put before Parliament for evaluation. In addition, over 200 parliamentarians reportedly sought to urge the Prime Minister to reconvene Parliament so as to deliberate the decision, indicating in a separate statement that the accord deprived MPs of their legislative role vis-a-vis the government.

On June 12, 2011, President Sharif Ahmed released a statement wherein he condemned the protests, describing them as "illegal". He also suggested that some government officials were financing the rallies in Mogadishu, and warned that the Al-Shabaab group of Islamists that is waging war against the federal government could try to exploit the gatherings to launch terrorist attacks.

In an interview on June 16, 2011, Undersecretary for Foreign Affairs of Italy, Alfredo Mantica, expressed support for Prime Minister Mohamed's position with regard to the Kampala agreement. Mantica stated that the Italian government believed that the accord ought to be reviewed in Parliament. He also indicated that "the prime minister has been in office five months. And [it is too] early to judge his work. But what he has done so far has been very positive. It has achieved important results. The government already seemed a miracle[...] The strength of the instability in Somalia is a constant. And the prime minister represents stability."

On June 19, 2011, Mohamed Abdullahi Mohamed resigned from his position as Prime Minister of Somalia. Part of the controversial Kampala Accord's conditions, the agreement would also see the mandates of the President, the Parliament Speaker and Deputies extended until August 2012, after which point new elections are to be organized. In his farewell speech, Prime Minister Mohamed indicated that he was stepping down in "the interest of the Somali people and the current situation in Somalia". He also thanked his Cabinet for its efforts in improving the security situation and the standards of governance in the country.

Abdiweli Mohamed Ali, Mohamed's former Minister of Planning and International Cooperation, was appointed as Acting Premier later the same day. A few days later, on June 23, 2011, Ali was named permanent Prime Minister.

Responding to the Kampala decision, the Al-Shabaab insurgent group's head of policy and regions, Sheikh Hussein Ali Fidow, told reporters on June 22, 2011 that the accord ended in failure since it was "an example [of how] the country is managed by Uganda" and that "it is clear for the Somali people and the international community that [the] Kampala meeting [on] Somalia was aimed to coerce the Prime Minister Mohamed Abdullahi Mohamed to step down". In addition, the spokesman suggested that Somalia's citizenry was aware of what was going on and that it did not recognize President Sharif Ahmed and the Parliament Speaker Sharif Hassan as legitimate governmental authorities. He also reiterated his group's call for Ugandan troops to withdraw from the country.

On June 24, 2011, lawmakers reaffirmed their opposition to and intention of repealing the Kampala decision. The Chairman of the federal Information, Public Awareness, Culture and Heritage Committee, Awad Ahmed Ashareh, indicated that 165 legislators had tendered a motion in Parliament opposing the agreement, but the Speaker rebuffed it. Ashareh also stated that MPs would issue a vote of no confidence vis-a-vis the Speaker Hassan if he continued to refuse to permit debate to take place, suggesting that Hassan's refusal "contravenes the Charter and rules of procedure."

Following talks with parliamentarians, President Sharif Ahmed asserted on June 28, 2011 that, on account of opposition amongst legislators to the Kampala decision, the accord would be brought before Parliament for deliberation. He also indicated that the agreement would not be implemented unless approved by lawmakers.

On May 25, 2010, Sharif Hassan was re-elected Speaker of the Transitional Federal Government's Parliament.

On October 14, 2010, President of Somalia Sheikh Sharif Sheikh Ahmed appointed former First Secretary in the Somali embassy in Washington, Mohamed Abdullahi Mohamed, as the nation's new Prime Minister. A row between Speaker of Parliament Sharif Hassan and the President then developed over whether the scheduled vote of confidence on Mohamed's nomination should be decided by a show of hands or via a secret ballot. Sharif Hassan favored a secret ballot while Sharif Ahmed preferred hand-raising, with the deciding voting session repeatedly postponed. The Supreme Court of Somalia subsequently ruled that the vote should be conducted by a show of hands, consistent with how previous confirmation votes in parliament had been decided since 1960. A delegation from the UN, AU and IGAD, including the Special Envoy to Somalia, also flew in to attempt to help resolve the impasse. On October 31, 2010, the vote of confidence was held, with lawmakers overwhelmingly approving Mohamed's appointment as Prime Minister. 297 of the 392 Members of Parliament endorsed the selection via hand-raising; 92 MPs voted against and 3 abstained. United Nations Secretary General Ban Ki-Moon also issued a statement commending the Somali leadership for having reached a consensus on procedural arrangements that facilitated a transparent and consultative confirmation of the new Premier.

On February 20, 2009, Sharif Hassan was appointed as Finance minister and Deputy Prime Minister of Somalia by Prime Minister Omar Abdirashid Ali Sharmarke.

On January 17, 2007, the Parliament voted to oust him due to his opposition of a peacekeeping force for Somalia and his expressions of support and unauthorized meetings with the Islamic Courts Union (ICU) which acted against the Transitional Federal Government (TFG) and his opposition to Ethiopian intervention in the 2006–2009 Somali War, with 183 votes against him, eight in favor and one abstention. Justice Minister Adan Mohamed Nuur became his successor in Parliamentary elections on January 31, 2007, and sworn in on February 3, 2007.

In 2005, Sheikh Sharif Hassan was opposed to the establishment of a new capital in Jowhar, which was the preference of President Abdullahi Yusuf Ahmed and Prime Minister Ali Mohammed Ghedi, demanding the capital be returned to Mogadishu. Baidoa was selected as a compromise location.

On October 6, 2005, he was quoted as saying, "In my view, Ethiopia does not want a functioning government in Somalia and I want to see that the world knows this. Even if Ethiopia does want a government here, it wants a fiefdom government - multiple governments which are all weak."