Stanley Sarnoff

Sarnoff died in 1990, awaiting a heart transplant. He was survived by his wife LoLo. At the last Annual Meeting during his lifetime, which was a few weeks prior to his death, many of the Fellows and their mentors gathered by the telephone to speak a few words to him and to thank him for the influence he had on their lives.

It was a revolutionary action. At that time, there were no other well known fellowships for medical students. In fact, the Sarnoff fellowship would form the basis for programs such as the AHA Student Research Scholarship program and the Howard Hughes NIH Research Scholars program, or cloisters program, which would not begin until 1984. For Sarnoff, what began with a single medical student fellow in 1979 spread to hundreds more.

As the fellowship grew, scientists with whom Stanley had collaborated suggested promising candidates and they were selected as Fellows. Early meetings were small gatherings at his home and at nearby hotels. The weekends were filled with students' presentations but also were informal gatherings and finished up with an afternoon of tennis at Stanley's home. The program was formalized in 1981 with the formation of The Stanley J. Sarnoff Endowment for Cardiovascular Science, Inc., a public charity. Many of the sponsors of the early Fellows were invited to serve on the Endowment's Board of Directors.

As STI prospered financially, Sarnoff was inspired to encourage young medical students to pursue cardiovascular research. He believed that a medical student could conduct his own research, defend his findings and participate in the work of the lab as a full-time scientist thereby allowing the student to yield great benefit from the lab environment. After discussions with Ellis Rolett, the chair of cardiology at Dartmouth, in 1979 Sarnoff agreed to meet four young medical students. He was so impressed by their enthusiasm that within one month Sarnoff writes a $10,000 check to Dartmouth to fund the first fellow.

After his training, Sarnoff spent a dozen years at the Harvard School of Public Health (1948–1960) as an assistant professor of physiology and he became chief of the cardiovascular physiology laboratory at the National Heart Institute (1954). At the NIH, Sarnoff published some of his most renowned papers in cardiac physiology. Sarnoff's first paper on ventricular function, published with Erik Berglund, was "Starling's Law of the Heart." After becoming chief of the cardiovascular physiology lab at NIH, he initiated a number of studies on valvular heart disease. A succession of prominent cardiac investigators work in Sarnoff's lab, including Eugene Braunwald, Joseph Gilmore, Jere Mitchell, William John Powell Jr, Edmund Sonnenblick, Andrew Wallace and Myron Weisfeldt. Sarnoff's experience mentoring Myron Weisfeldt, who was then a young medical student from Johns Hopkins, spurred him to begin his philanthropic efforts toward medical students.

A graduate of the Peddie School, Sarnoff received his undergraduate degree from Princeton University (1938) and his medical degree form Johns Hopkins University School of Medicine (1942). Although he was interested in research as a medical student, Sarnoff was strongly encouraged to become a cardiac surgeon by his father, Jacob Sarnoff, who was a prominent surgeon of the time. While Sarnoff was assisting his father in the operating room, he made observations which challenged conventional thoughts on cardiac physiology. The observations he made on that day became the foundation of his bench research and changed the way cardiology was practiced. After his residency, Sarnoff completed post graduate training at Bellevue Hospital (New York), Beth Israel Hospital (Boston), Mount Sinai Hospital (New York), and Harvard Medical School.

Stanley J. Sarnoff (April 5, 1917 – May 23, 1990) was an American doctor who produced over 200 papers and 60 patents during his long career. His work included the development of such widely used devices as the "auto-injector," which included the AtroPen, which was filled with Atropine Hydrochloride as an anti-nerve-gas antidote for military use; the LidoPen, which was filled with Lidocaine hydrochloride, for cardiac patients, the EpiPen, containing Epinephrine, for people whose allergies cause anaphylaxis, and the 24-hour cardiac monitor. In addition to his own work, he was devoted to philanthropy and, though the creation of The Stanley J Sarnoff Endowment for Cardiovascular Science, he has helped to inspire medical students and cardiology fellows from around the country to pursue cardiovascular research.