Thomas A. Steitz

Steitz was married to Joan A. Steitz, a distinguished molecular biologist who is also a Sterling Professor of Molecular Biophysics and Biochemistry at Yale. He lived with her in Branford, Connecticut and had one son, Jon. He died on October 9, 2018 of complications during treatment of pancreatic cancer.

Steitz was awarded the 2009 Nobel Prize in Chemistry along with Venkatraman Ramakrishnan and Ada Yonath "for studies of the structure and function of the ribosome". Steitz also won the Gairdner International Award in 2007 "for his studies on the structure and function of the ribosome which showed that the peptidyl transferase was an RNA catalyzed reaction, and for revealing the mechanism of inhibition of this function by antibiotics".

He was also a Macy Fellow at the University of Göttingen during 1976–1977 and a Fairchild Scholar at the California Institute of Technology during 1984-1985.

Both Tom and Joan Steitz instead joined the Yale faculty in 1970, where he continued to work on cellular and structural biology. Steitz and Peter Moore determined the atomic structure of the large 50S ribosomal subunit using X-ray crystallography, and published their findings in Science in 2000. In 2009, Steitz was awarded the Nobel Prize in Chemistry for his ribosome research.

Steitz did postdoctoral research as a Jane Coffin Childs Postdoctoral Fellow at the MRC Laboratory of Molecular Biology at the University of Cambridge during 1967–1970.

He received a Ph.D. in biochemistry and molecular biology from Harvard University in 1966 where he worked under the direction of subsequent 1976 chemistry Nobel Prize winner William N. Lipscomb, Jr. While at Harvard, after the training task of determining the structure of the small molecule methyl ethylene phosphate, Steitz made contributions to determining the atomic structures of carboxypeptidase A and aspartate carbamoyltransferase, each the largest atomic structure determined in its time.

Born in Milwaukee, Wisconsin, Steitz studied chemistry as an undergraduate at Lawrence University in Appleton, Wisconsin, graduating in 1962. While there he was a member of the fraternity, Delta Tau Delta, the Delta Nu chapter. In June 2010, the University renamed its chemistry building Thomas A. Steitz Hall of Science.

Thomas Arthur Steitz (August 23, 1940 – October 9, 2018) was an American biochemist, a Sterling Professor of Molecular Biophysics and Biochemistry at Yale University, and investigator at the Howard Hughes Medical Institute, best known for his pioneering work on the ribosome.